Here we describe the functionalization of lupulone natural compound in obtaining 3-isobutyl-5,5,7-tris(3-methylbut-2-en-1-yl)-1-phenyl-1,7-dihydro-4H-indazole-4,6(5H)-dione.The lupulone-H-indazole derivative was prepared with 75% yield through the reaction between lupulone and phenyl-hydrazine employing SiO2/ZnCl2 (30% m/m) as a support solid in a
BACKGROUND: Association of mitochondrial haplogroup J with longevity has been reported in several population subgroups.While studies from northern Italy and Finland, have described a higher frequency Onion Soup Bowls of haplogroup J among centenarians in comparison to non-centenarian, several other studies could not replicate these results and sugg
This work presents a meta-analysis that compares the suitability of various parameters used to characterize wettability in tribological systems.It also examines the relationship between wettability and the friction factor for multiple lubricant-surface pairings.The characterization of wetting behavior was similar when using the contact angle betwee
While the physical interactions between the Golgi apparatus (Golgi) and lipid droplets (LDs) have been suggested through system-level imaging, the Golgi-LD membrane contact sites (MCSs) remain largely uncharacterized.Here, we BROW PENCIL BRUNETTE #1610 show evidence to support the existence of Golgi-LD MCSs in HEK293 cells.We further suggest that v